If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. Checkbox not checked

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).




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SCHEDULE 13D




Comment for Type of Reporting Person:
The shares listed in rows 8, 10 and 11 consists of (i) 6,829,524 Ordinary Shares and (ii) 500,333 Ordinary Shares that are issuable upon the exercise of warrants, each to acquire one Ordinary Share ("Warrants"). The percentage listed in row 13 is calculated based on (i) 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026, as increased by (ii) 500,333 Ordinary Shares issuable upon the exercise of Warrants.


SCHEDULE 13D




Comment for Type of Reporting Person:
The shares listed in rows 8, 10 and 11 consists of (i) 3,801,000 Ordinary Shares and (ii) 167,000 Ordinary Shares that are issuable upon the exercise of Warrants. The percentage listed in row 13 is calculated based on (i) 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026, as increased by (ii) 500,333 Ordinary Shares issuable upon the exercise of Warrants.


SCHEDULE 13D




Comment for Type of Reporting Person:
The shares listed in rows 8, 10 and 11 consists of (i) 6,829,524 Ordinary Shares and (ii) 500,333 Ordinary Shares that are issuable upon the exercise of Warrants. The percentage listed in row 13 is calculated based on (i) 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026, as increased by (ii) 500,333 Ordinary Shares issuable upon the exercise of Warrants.


SCHEDULE 13D




Comment for Type of Reporting Person:
The shares listed in rows 8, 10 and 11 consists of (i) 6,829,524 Ordinary Shares and (ii) 500,333 Ordinary Shares that are issuable upon the exercise of Warrants. The percentage listed in row 13 is calculated based on (i) 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026, as increased by (ii) 500,333 Ordinary Shares issuable upon the exercise of Warrants.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The percentage listed in row 13 is calculated based on 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026.


SCHEDULE 13D




Comment for Type of Reporting Person:
The shares listed in rows 8, 10 and 11 consists of (i) 3,801,000 Ordinary Shares held directly by Frazier Lifesciences Sponsor LLC, (ii) 167,700 Ordinary Shares that are issuable upon the exercise of Warrants held directly by Frazier Lifesciences Sponsor LLC, (iii) 3,028,524 Ordinary Shares held directly by Frazier Life Sciences X, L.P. and (iv) 333,333 Ordinary Shares that are issuable upon the exercise of Warrants held directly by Frazier Life Sciences X, L.P. The percentage listed in row 13 is calculated based on (i) 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026, as increased by (ii) 500,333 Ordinary Shares issuable upon the exercise of Warrants held collectively by Frazier Lifesciences Sponsor LLC and Frazier Life Sciences X, L.P.


SCHEDULE 13D




Comment for Type of Reporting Person:
The shares listed in rows 8, 10 and 11 consists of (i) 3,801,000 Ordinary Shares held directly by Frazier Lifesciences Sponsor LLC, (ii) 167,700 Ordinary Shares that are issuable upon the exercise of Warrants held directly by Frazier Lifesciences Sponsor LLC, (iii) 3,028,524 Ordinary Shares held directly by Frazier Life Sciences X, L.P. and (iv) 333,333 Ordinary Shares that are issuable upon the exercise of Warrants held directly by Frazier Life Sciences X, L.P. The percentage listed in row 13 is calculated based on (i) 119,537,169 Ordinary Shares that were outstanding as of August 3, 2026, as reported in the Issuer's Quarterly Report on Form 10-Q filed with the SEC on August 5, 2026, as increased by (ii) 500,333 Ordinary Shares issuable upon the exercise of Warrants held collectively by Frazier Lifesciences Sponsor LLC and Frazier Life Sciences X, L.P.


SCHEDULE 13D


 
Frazier Life Sciences X, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS X, L.L.C., GP of FHMLS X, L.P., GP of Frazier Life Sciences X, L.P.
Date:09/22/2026
 
Frazier Lifesciences Sponsor LLC
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS X, L.L.C., GP of FHMLS X, L.P., GP of Frazier Life Sciences X, L.P., Sole Member of Frazier Lifesciences Sponsor LLC
Date:09/22/2026
 
FHMLS X, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS X, L.L.C., GP of FHMLS X, L.P.
Date:09/22/2026
 
FHMLS X, L.L.C.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS X, L.L.C.
Date:09/22/2026
 
Frazier Life Sciences Public Fund, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLSP, L.L.C., GP of FHMLSP, L.P., GP of Frazier Life Sciences Public Fund, L.P.
Date:09/22/2026
 
FHMLSP, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLSP, L.L.C., GP of FHMLSP, L.P.
Date:09/22/2026
 
FHMLSP, L.L.C.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLSP, L.L.C.
Date:09/22/2026
 
Frazier Life Sciences XI, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XI, L.L.C., GP of FHMLS XI, L.P., GP of Frazier Life Sciences XI, L.P.
Date:09/22/2026
 
FHMLS XI, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XI, L.L.C., GP of FHMLS XI, L.P.
Date:09/22/2026
 
FHMLS XI, L.L.C.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XI, L.L.C.
Date:09/22/2026
 
Frazier Life Sciences XII, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XII, L.L.C., GP of FHMLS XII, L.P., GP of Frazier Life Sciences XII, L.P.
Date:09/22/2026
 
FHMLS XII, L.P.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XII, L.L.C., GP of FHMLS XII, L.P.
Date:09/22/2026
 
FHMLS XII, L.L.C.
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, CFO of FHMLS XII, L.L.C.
Date:09/22/2026
 
James N. Topper
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, Attorney-in-Fact for James N. Topper, pursuant to a Power of Attorney
Date:09/22/2026
 
Patrick J. Heron
 
Signature:/s/ Jennifer Martin
Name/Title:By Jennifer Martin, Attorney-in-Fact for Patrick J. Heron, pursuant to a Power of Attorney
Date:09/22/2026
ex-10-09222026_080956.htm

EXHIBIT 10.1


Transactions Relating to the Ordinary Shares of the Issuer During the Past Sixty (60) Days


The following table sets forth all transactions relating to the Ordinary Shares of the Issuer that were effected during the past sixty (60) days by the applicable Reporting Person.


Reporting Person Name

Date of Event

Type of Transaction

Number of Shares

Weighted Average Price

Low Price

High Price

FLSPF

9/8/2026

Purchase

92,220

$25.1950

$24.68

$25.50

FLS XI

9/8/2026

Purchase

1,210

$25.1950

$24.68

$25.50

FLS XII

9/8/2026

Purchase

6,570

$25.1950

$24.68

$25.50

FLSPF

9/9/2026

Purchase

119,619

$22.7696

$22.34

$23.335

FLS XI

9/9/2026

Purchase

1,569

$22.7696

$22.34

$23.335

FLS XII

9/9/2026

Purchase

8,522

$22.7696

$22.34

$23.335

FLSPF

9/9/2026

Purchase

18,711

$23.6256

$23.34

$24.045

FLS XI

9/9/2026

Purchase

246

$23.6256

$23.34

$24.045

FLS XII

9/9/2026

Purchase

1,333

$23.6256

$23.34

$24.045

FLSPF

9/9/2026

Purchase

46,110

$24.5308

$24.365

$24.645

FLS XI

9/9/2026

Purchase

605

$24.5308

$24.365

$24.645

FLS XII

9/9/2026

Purchase

3,285

$24.5308

$24.365

$24.645

FLSPF

9/10/2026

Purchase

89,827

$22.3614

$21.805

$22.80

FLS XI

9/10/2026

Purchase

1,179

$22.3614

$21.805

$22.80

FLS XII

9/10/2026

Purchase

6,400

$22.3614

$21.805

$22.80

FLSPF

9/10/2026

Purchase

2,393

$22.8579

$22.81

$22.935

FLS XI

9/10/2026

Purchase

31

$22.8579

$22.81

$22.935

FLS XII

9/10/2026

Purchase

170

$22.8579

$22.81

$22.935

FLSPF

9/14/2026

Purchase

92,220

$22.6765

$22.57

$22.80

FLS XI

9/14/2026

Purchase

1,210

$22.6765

$22.57

$22.80

FLS XII

9/14/2026

Purchase

6,570

$22.6765

$22.57

$22.80

FLSPF

9/15/2026

Purchase

92,220

$21.4052

$21.08

$22.065

FLS XI

9/15/2026

Purchase

1,210

$21.4052

$21.08

$22.065

FLS XII

9/15/2026

Purchase

6,570

$21.4052

$21.08

$22.065

FLSPF

9/16/2026

Purchase

92,220

$21.1853

$21.08

$21.31

FLS XI

9/16/2026

Purchase

1,210

$21.1853

$21.08

$21.31

FLS XII

9/16/2026

Purchase

6,570

$21.1853

$21.08

$21.31

FLSPF

9/17/2026

Purchase

46,110

$21.8749

$21.54

$21.91

FLS XI

9/17/2026

Purchase

605

$21.8749

$21.54

$21.91

FLS XII

9/17/2026

Purchase

3,285

$21.8749

$21.54

$21.91

FLSPF

9/18/2026

Purchase

79,684

$21.7194

$21.40

$22.3953

FLS XI

9/18/2026

Purchase

1,046

$21.7194

$21.40

$22.3953

FLS XII

9/18/2026

Purchase

5,677

$21.7194

$21.40

$22.3953

 

 

 

 

 

 

 





FLSPF

9/18/2026

Purchase

12,536

$22.4361

$22.40

$22.47

FLS XI

9/18/2026

Purchase

164

$22.4361

$22.40

$22.47

FLS XII

9/18/2026

Purchase

893

$22.4361

$22.40

$22.47


Each of FLSPF, FLS XI and FLS XII undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth above.